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nadph 4na  (Chem Impex International)


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    Chem Impex International nadph 4na
    Nadph 4na, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nadph+4na/b-Nicotinamide+adenine+dinucleotide+phosphate+reduced+form%2C+tetrasodium+salt/us12583838-1156-11-14
    Average 95 stars, based on 15 article reviews
    nadph 4na - by Bioz Stars, 2026-10
    95/100 stars

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    Article Title: Analogs for the treatment of disease
    Article Snippet: Materials: NADPH powder: p-Nicotinamide adenine dinucleotide phosphate reduced form, tetrasodium salt; NADPH 4Na (Vendor: Chem-Impex International, Cat. No. 00616).

    Article Title: Analogs for the treatment of disease
    Article Snippet: Materials: NADPH powder: β-Nicotinamide adenine dinucleotide phosphate reduced form, tetrasodium salt; NADPH·4Na (Vendor: Chem-Impex International, Cat. No. 00616).

    Article Title: Macrocyclic compounds and compositions, and methods of preparing and using the same
    Article Snippet: NADPH Cofactor Preparation: Materials: NADPH powder: β-Nicotinamide adenine dinucleotide phosphate reduced form, tetrasodium salt; NADPH·4Na (Vendor: Chem-Impex International, Cat. No. 00616).

    Article Title: Analogs for the treatment of disease
    Article Snippet: Materials: NADPH powder: β-Nicotinamide adenine dinucleotide phosphate reduced form, tetrasodium salt; NADPH.4Na (Vendor: Chem-Impex International, Cat. No. 00616).

    Article Title: Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators.
    Article Snippet: Materials NADPH powder: β-Nicotinamide adenine dinucleotide phosphate reduced form, tetrasodium salt; NADPH·4Na (Vendor: Chem-Impex International, Cat. No. 00616).



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    GENTAUR Inc nicotinamide adenine dinucleotide phosphate tetrasodium (nadph.4na)
    Human metabolic pathways of aflatoxin B1 (AFB1). Aflatoxin M1 (AFM1) is formed by CYP1A2, aflatoxin P1 (AFP1) by CYP2A13, CYP2A3, and CYP321A1. Aflatoxin-8,9-endo/exo-epoxides (AFBO) are formed by both CYP1A2 and CYP3A4. More downstream metabolites of AFBO are depicted without a frame (aflatoxin B-N 7 -guanine (AFB-N 7 -gua), aflatoxin B-formamidopyridine (AFB-FAPyr), aflatoxin B-diol (AFB-diol), aflatoxin B-dialdehyde (AFB-dialdehyde), aflatoxin B-S-glutathion (AFB-GSH), aflatoxin B-mercapturic acid (AFB-NAC), aflatoxin B1-lysine (AFB-lysine), aflatoxin B-monoalcohols (AFB-monoalcohols), and aflatoxin B dialcohol (AFB-dialcohol)). Aflatoxin B2a (AFB2a) is formed by the involvement of CYP450 enzymes, not further specified. Aflatoxin Q1 (AFQ1) is formed by CYP3A4 and CYP3A5. Aflatoxicol (AFL) is produced by <t>nicotinamide-adenine-dinucleotide</t> phosphate reductase (NADPH reductase). Both AFL and AFQ1 can form aflatoxicol H1 (AFH1). Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor drug and CYP3A4 inducer, is also presented, indicating its inducing effect on CYP3A4, expected to increase the formation of both AFQ1 and AFBO (green frames) . The toxic metabolites of AFB1 are presented in thick grey frames (AFM1 and AFBO).
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    Human metabolic pathways of aflatoxin B1 (AFB1). Aflatoxin M1 (AFM1) is formed by CYP1A2, aflatoxin P1 (AFP1) by CYP2A13, CYP2A3, and CYP321A1. Aflatoxin-8,9-endo/exo-epoxides (AFBO) are formed by both CYP1A2 and CYP3A4. More downstream metabolites of AFBO are depicted without a frame (aflatoxin B-N 7 -guanine (AFB-N 7 -gua), aflatoxin B-formamidopyridine (AFB-FAPyr), aflatoxin B-diol (AFB-diol), aflatoxin B-dialdehyde (AFB-dialdehyde), aflatoxin B-S-glutathion (AFB-GSH), aflatoxin B-mercapturic acid (AFB-NAC), aflatoxin B1-lysine (AFB-lysine), aflatoxin B-monoalcohols (AFB-monoalcohols), and aflatoxin B dialcohol (AFB-dialcohol)). Aflatoxin B2a (AFB2a) is formed by the involvement of CYP450 enzymes, not further specified. Aflatoxin Q1 (AFQ1) is formed by CYP3A4 and CYP3A5. Aflatoxicol (AFL) is produced by nicotinamide-adenine-dinucleotide phosphate reductase (NADPH reductase). Both AFL and AFQ1 can form aflatoxicol H1 (AFH1). Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor drug and CYP3A4 inducer, is also presented, indicating its inducing effect on CYP3A4, expected to increase the formation of both AFQ1 and AFBO (green frames) . The toxic metabolites of AFB1 are presented in thick grey frames (AFM1 and AFBO).

    Journal: Toxins

    Article Title: Exploring the Impact of Efavirenz on Aflatoxin B1 Metabolism: Insights from a Physiologically Based Pharmacokinetic Model and a Human Liver Microsome Study

    doi: 10.3390/toxins16060259

    Figure Lengend Snippet: Human metabolic pathways of aflatoxin B1 (AFB1). Aflatoxin M1 (AFM1) is formed by CYP1A2, aflatoxin P1 (AFP1) by CYP2A13, CYP2A3, and CYP321A1. Aflatoxin-8,9-endo/exo-epoxides (AFBO) are formed by both CYP1A2 and CYP3A4. More downstream metabolites of AFBO are depicted without a frame (aflatoxin B-N 7 -guanine (AFB-N 7 -gua), aflatoxin B-formamidopyridine (AFB-FAPyr), aflatoxin B-diol (AFB-diol), aflatoxin B-dialdehyde (AFB-dialdehyde), aflatoxin B-S-glutathion (AFB-GSH), aflatoxin B-mercapturic acid (AFB-NAC), aflatoxin B1-lysine (AFB-lysine), aflatoxin B-monoalcohols (AFB-monoalcohols), and aflatoxin B dialcohol (AFB-dialcohol)). Aflatoxin B2a (AFB2a) is formed by the involvement of CYP450 enzymes, not further specified. Aflatoxin Q1 (AFQ1) is formed by CYP3A4 and CYP3A5. Aflatoxicol (AFL) is produced by nicotinamide-adenine-dinucleotide phosphate reductase (NADPH reductase). Both AFL and AFQ1 can form aflatoxicol H1 (AFH1). Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor drug and CYP3A4 inducer, is also presented, indicating its inducing effect on CYP3A4, expected to increase the formation of both AFQ1 and AFBO (green frames) . The toxic metabolites of AFB1 are presented in thick grey frames (AFM1 and AFBO).

    Article Snippet: Nicotinamide adenine dinucleotide phosphate tetrasodium (NADPH.4Na) was retrieved from Gentaur (Kampenhout, Belgium) and stored at −20 °C.

    Techniques: Produced, Reverse Transcription